Beneficial impact of Gpnmb and its significance as a biomarker in nonalcoholic steatohepatitis

Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease worldwide. Gpnmb is classified as a type 1 membrane protein and its soluble form is secreted by ADAM10-mediated cleavage. Gpnmb mRNA was found in the Kupffer cells and white adipose tissues (WATs) and its upre...

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Publicado no:Sci Rep
Main Authors: Katayama, Akihiro, Nakatsuka, Atsuko, Eguchi, Jun, Murakami, Kazutoshi, Teshigawara, Sanae, Kanzaki, Motoko, Nunoue, Tomokazu, Hida, Kazuyuki, Wada, Nozomu, Yasunaka, Tetsuya, Ikeda, Fusao, Takaki, Akinobu, Yamamoto, Kazuhide, Kiyonari, Hiroshi, Makino, Hirofumi, Wada, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652285/
https://ncbi.nlm.nih.gov/pubmed/26581806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16920
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