Serum galectin-9 levels are elevated in the patients with type 2 diabetes and chronic kidney disease

BACKGROUND: Galectin-9 (Gal-9) induces apoptosis in activated T helper 1 (T(H)1) cells as a ligand for T cell immunoglobulin mucin-3 (Tim-3). Gal-9 also inhibits the G1 phase cell cycle arrest and hypertrophy in db/db mice, the hallmark of early diabetic nephropathy, by reversing the high glucose-in...

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Main Authors: Kurose, Yuko, Wada, Jun, Kanzaki, Motoko, Teshigawara, Sanae, Nakatsuka, Atsuko, Murakami, Kazutoshi, Inoue, Kentaro, Terami, Takahiro, Katayama, Akihiro, Watanabe, Mayu, Higuchi, Chigusa, Eguchi, Jun, Miyatake, Nobuyuki, Makino, Hirofumi
格式: Artigo
語言:Inglês
出版: BioMed Central 2013
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556305/
https://ncbi.nlm.nih.gov/pubmed/23339460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2369-14-23
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