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Pemt Deficiency Ameliorates Endoplasmic Reticulum Stress in Diabetic Nephropathy
Phosphatidylethanolamine N-methyltransferase (Pemt) catalyzes the methylation of phosphatidylethanolamine (PE) to phosphatidylcholine (PC) mainly in the liver. Under an obese state, the upregulation of Pemt induces endoplasmic reticulum (ER) stress by increasing the PC/PE ratio in the liver. We targ...
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| Main Authors: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3965443/ https://ncbi.nlm.nih.gov/pubmed/24667182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092647 |
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