Disorder in a two-domain neuronal Ca(2+)-binding protein regulates domain stability and dynamics using ligand mimicry

Understanding the interplay between sequence, structure and function of proteins has been complicated in recent years by the discovery of intrinsically disordered proteins (IDPs), which perform biological functions in the absence of a well-defined three-dimensional fold. Disordered protein sequences...

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Bibliographic Details
Published in:Cell Mol Life Sci
Main Authors: Staby, Lasse, Kemplen, Katherine R., Stein, Amelie, Ploug, Michael, Clarke, Jane, Skriver, Karen, Heidarsson, Pétur O., Kragelund, Birthe B.
Format: Artigo
Language:Inglês
Published: Springer International Publishing 2020
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7966663/
https://ncbi.nlm.nih.gov/pubmed/32936312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-020-03639-z
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