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Effects of Ligand Binding on the Energy Landscape of Acyl-CoA-Binding Protein
Binding of ligands is often crucial for function yet the effects of ligand binding on the mechanical stability and energy landscape of proteins are incompletely understood. Here, we use a combination of single-molecule optical tweezers and MD simulations to investigate the effect of ligand binding o...
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| Pubblicato in: | Biophys J |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Biophysical Society
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7677128/ https://ncbi.nlm.nih.gov/pubmed/33080224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.09.016 |
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