Hypoxanthine Induces Muscular ATP Depletion and Fatigue via UCP2

Hypoxanthine (Hx), an intermediate metabolite of the purine metabolism pathway which is dramatically increased in blood and skeletal muscle during muscle contraction and metabolism, is characterized as a marker of exercise exhaustion. However, the physiological effects of Hx on skeletal muscle remai...

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Détails bibliographiques
Publié dans:Front Physiol
Auteurs principaux: Yin, Cong, Ma, Zewei, Li, Fan, Duan, Chen, Yuan, Yexian, Zhu, Canjun, Wang, Lina, Zhu, Xiaotong, Wang, Songbo, Gao, Ping, Shu, Gang, Zhang, Huihua, Jiang, Qingyan
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2021
Sujets:
Physiology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7966526/
https://ncbi.nlm.nih.gov/pubmed/33746782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2021.647743
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