α-Ketoglutarate prevents skeletal muscle protein degradation and muscle atrophy through PHD3/ADRB2 pathway

Skeletal muscle atrophy due to excessive protein degradation is the main cause for muscle dysfunction, fatigue, and weakening of athletic ability. Endurance exercise is effective to attenuate muscle atrophy, but the underlying mechanism has not been fully investigated. α-Ketoglutarate (AKG) is a key...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Cai, Xingcai, Yuan, Yexian, Liao, Zhengrui, Xing, Kongping, Zhu, Canjun, Xu, Yaqiong, Yu, Lulu, Wang, Lina, Wang, Songbo, Zhu, Xiaotong, Gao, Ping, Zhang, Yongliang, Jiang, Qingyan, Xu, Pingwen, Shu, Gang
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6266637/
https://ncbi.nlm.nih.gov/pubmed/28939592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700670R
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