α-Ketoglutarate prevents skeletal muscle protein degradation and muscle atrophy through PHD3/ADRB2 pathway

Skeletal muscle atrophy due to excessive protein degradation is the main cause for muscle dysfunction, fatigue, and weakening of athletic ability. Endurance exercise is effective to attenuate muscle atrophy, but the underlying mechanism has not been fully investigated. α-Ketoglutarate (AKG) is a key...

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Dades bibliogràfiques
Publicat a:FASEB J
Autors principals: Cai, Xingcai, Yuan, Yexian, Liao, Zhengrui, Xing, Kongping, Zhu, Canjun, Xu, Yaqiong, Yu, Lulu, Wang, Lina, Wang, Songbo, Zhu, Xiaotong, Gao, Ping, Zhang, Yongliang, Jiang, Qingyan, Xu, Pingwen, Shu, Gang
Format: Artigo
Idioma:Inglês
Publicat: Federation of American Societies for Experimental Biology 2018
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6266637/
https://ncbi.nlm.nih.gov/pubmed/28939592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700670R
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