α-Ketoglutarate prevents skeletal muscle protein degradation and muscle atrophy through PHD3/ADRB2 pathway

Skeletal muscle atrophy due to excessive protein degradation is the main cause for muscle dysfunction, fatigue, and weakening of athletic ability. Endurance exercise is effective to attenuate muscle atrophy, but the underlying mechanism has not been fully investigated. α-Ketoglutarate (AKG) is a key...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:FASEB J
Κύριοι συγγραφείς: Cai, Xingcai, Yuan, Yexian, Liao, Zhengrui, Xing, Kongping, Zhu, Canjun, Xu, Yaqiong, Yu, Lulu, Wang, Lina, Wang, Songbo, Zhu, Xiaotong, Gao, Ping, Zhang, Yongliang, Jiang, Qingyan, Xu, Pingwen, Shu, Gang
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Federation of American Societies for Experimental Biology 2018
Θέματα:
Research
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6266637/
https://ncbi.nlm.nih.gov/pubmed/28939592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700670R
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