Exercise‐induced α‐ketoglutaric acid stimulates muscle hypertrophy and fat loss through OXGR1‐dependent adrenal activation

Beneficial effects of resistance exercise on metabolic health and particularly muscle hypertrophy and fat loss are well established, but the underlying chemical and physiological mechanisms are not fully understood. Here, we identified a myometabolite‐mediated metabolic pathway that is essential for...

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Publicado en:EMBO J
Main Authors: Yuan, Yexian, Xu, Pingwen, Jiang, Qingyan, Cai, Xingcai, Wang, Tao, Peng, Wentong, Sun, Jiajie, Zhu, Canjun, Zhang, Cha, Yue, Dong, He, Zhihui, Yang, Jinping, Zeng, Yuxian, Du, Man, Zhang, Fenglin, Ibrahimi, Lucas, Schaul, Sarah, Jiang, Yuwei, Wang, Jiqiu, Sun, Jia, Wang, Qiaoping, Liu, Liming, Wang, Songbo, Wang, Lina, Zhu, Xiaotong, Gao, Ping, Xi, Qianyun, Yin, Cong, Li, Fan, Xu, Guli, Zhang, Yongliang, Shu, Gang
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2020
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7110140/
https://ncbi.nlm.nih.gov/pubmed/32104923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019103304
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