Hypoxanthine Induces Muscular ATP Depletion and Fatigue via UCP2

Hypoxanthine (Hx), an intermediate metabolite of the purine metabolism pathway which is dramatically increased in blood and skeletal muscle during muscle contraction and metabolism, is characterized as a marker of exercise exhaustion. However, the physiological effects of Hx on skeletal muscle remai...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Yin, Cong, Ma, Zewei, Li, Fan, Duan, Chen, Yuan, Yexian, Zhu, Canjun, Wang, Lina, Zhu, Xiaotong, Wang, Songbo, Gao, Ping, Shu, Gang, Zhang, Huihua, Jiang, Qingyan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7966526/
https://ncbi.nlm.nih.gov/pubmed/33746782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2021.647743
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