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The transport pathway in the ABCG2 protein and its regulation revealed by molecular dynamics simulations

Atomic-level structural insight on the human ABCG2 membrane protein, a pharmacologically important transporter, has been recently revealed by several key papers. In spite of the wealth of structural data, the pathway of transmembrane movement for the large variety of structurally different ABCG2 sub...

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Publicat a:Cell Mol Life Sci
Autors principals: Nagy, Tamás, Tóth, Ágota, Telbisz, Ágnes, Sarkadi, Balázs, Tordai, Hedvig, Tordai, Attila, Hegedűs, Tamás
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7966132/
https://ncbi.nlm.nih.gov/pubmed/32979053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-020-03651-3
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