Cellular expression and function of naturally occurring variants of the human ABCG2 multidrug transporter

The human ABCG2 multidrug transporter plays a crucial role in the absorption and excretion of xeno- and endobiotics; thus the relatively frequent polymorphic and mutant ABCG2 variants in the population may significantly alter disease conditions and pharmacological effects. Low-level or non-functiona...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cell Mol Life Sci
Auteurs principaux: Zámbó, Boglárka, Mózner, Orsolya, Bartos, Zsuzsa, Török, György, Várady, György, Telbisz, Ágnes, Homolya, László, Orbán, Tamás I., Sarkadi, Balázs
Format: Artigo
Langue:Inglês
Publié: Springer International Publishing 2019
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6971004/
https://ncbi.nlm.nih.gov/pubmed/31254042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-019-03186-2
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