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Cellular Processing of the ABCG2 Transporter—Potential Effects on Gout and Drug Metabolism

The human ABCG2 is an important plasma membrane multidrug transporter, involved in uric acid secretion, modulation of absorption of drugs, and in drug resistance of cancer cells. Variants of the ABCG2 transporter, affecting cellular processing and trafficking, have been shown to cause gout and incre...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Mózner, Orsolya, Bartos, Zsuzsa, Zámbó, Boglárka, Homolya, László, Hegedűs, Tamás, Sarkadi, Balázs
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6830335/
https://ncbi.nlm.nih.gov/pubmed/31597297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8101215
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