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Survival and Pulmonary Injury After Neonatal Sepsis: PD1/PDL1's Contributions to Mouse and Human Immunopathology
Morbidity and mortality associated with neonatal sepsis remains a healthcare crisis. PD1(−/−) neonatal mice endured experimental sepsis, in the form of cecal slurry (CS), and showed improved rates of survival compared to wildtype (WT) counterparts. End-organ injury, particularly of the lung, contrib...
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| 出版年: | Front Immunol |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Frontiers Media S.A.
2021
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7965961/ https://ncbi.nlm.nih.gov/pubmed/33746973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.634529 |
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