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Trisomy 21 impairs PGE2 production in dermal fibroblasts

The triplication of human chromosome 21 results in Down syndrome (DS), the most common genetic form of intellectual disability. This aneuploid condition also results in an enhanced risk of a spectrum of comorbid conditions, such as leukemia, early onset Alzheimer’s disease, and diabetes. Individuals...

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Bibliografische gegevens
Gepubliceerd in:Prostaglandins Other Lipid Mediat
Hoofdauteurs: Marentette, John O., Anderson, Colin C., Prutton, Kendra M., Jennings, Erin Q., Rauniyar, Abhishek K., Galligan, James J., Roede, James R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7965340/
https://ncbi.nlm.nih.gov/pubmed/33418267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2020.106524
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