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Consequences of aneuploidy in human fibroblasts with trisomy 21

An extra copy of chromosome 21 causes Down syndrome, the most common genetic disease in humans. The mechanisms contributing to aneuploidy-related pathologies in this syndrome, independent of the identity of the triplicated genes, are not well defined. To characterize aneuploidy-driven phenotypes in...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Hwang, Sunyoung, Cavaliere, Paola, Li, Rui, Zhu, Lihua Julie, Dephoure, Noah, Torres, Eduardo M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8017964/
https://ncbi.nlm.nih.gov/pubmed/33526671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2014723118
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