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Suppressing Aneuploidy-Associated Phenotypes Improves the Fitness of Trisomy 21 Cells
An abnormal number of chromosomes, or aneuploidy, accounts for most spontaneous abortions, causes developmental defects, and is associated with aging and cancer. The molecular mechanisms by which aneuploidy disrupts cellular function remain largely unknown. Here, we show that aneuploidy disrupts the...
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| Publicado no: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6886690/ https://ncbi.nlm.nih.gov/pubmed/31747614 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.10.059 |
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