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Suppressing Aneuploidy-Associated Phenotypes Improves the Fitness of Trisomy 21 Cells
An abnormal number of chromosomes, or aneuploidy, accounts for most spontaneous abortions, causes developmental defects, and is associated with aging and cancer. The molecular mechanisms by which aneuploidy disrupts cellular function remain largely unknown. Here, we show that aneuploidy disrupts the...
Tallennettuna:
| Julkaisussa: | Cell Rep |
|---|---|
| Päätekijät: | , , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2019
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6886690/ https://ncbi.nlm.nih.gov/pubmed/31747614 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.10.059 |
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