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Evolution of aneuploidy: overcoming the original CIN

Chromosomal instability (CIN) generates continuously novel aneuploid genomes—unbalanced chromosome combinations that differ from the haploid chromosome set and its multiples. On one hand, this causes problems for cells, as high CIN and aneuploidy impair cellular proliferation by inducing multiple ce...

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Vydáno v:Genes Dev
Hlavní autor: Storchova, Zuzana
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6295170/
https://ncbi.nlm.nih.gov/pubmed/30509947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.321810.118
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