Bardet–Biedl syndrome 3 protein promotes ciliary exit of the signaling protein phospholipase D via the BBSome

Certain ciliary signaling proteins couple with the BBSome, a conserved complex of Bardet–Biedl syndrome (BBS) proteins, to load onto retrograde intraflagellar transport (IFT) trains for their removal out of cilia in Chlamydomonas reinhardtii. Here, we show that loss of the Arf-like 6 (ARL6) GTPase B...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Liu, Yan-Xia, Xue, Bin, Sun, Wei-Yue, Wingfield, Jenna L, Sun, Jun, Wu, Mingfu, Lechtreck, Karl F, Wu, Zhenlong, Fan, Zhen-Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2021
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7963478/
https://ncbi.nlm.nih.gov/pubmed/33587040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.59119
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