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Bardet–Biedl syndrome 3 protein promotes ciliary exit of the signaling protein phospholipase D via the BBSome

Certain ciliary signaling proteins couple with the BBSome, a conserved complex of Bardet–Biedl syndrome (BBS) proteins, to load onto retrograde intraflagellar transport (IFT) trains for their removal out of cilia in Chlamydomonas reinhardtii. Here, we show that loss of the Arf-like 6 (ARL6) GTPase B...

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Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Liu, Yan-Xia, Xue, Bin, Sun, Wei-Yue, Wingfield, Jenna L, Sun, Jun, Wu, Mingfu, Lechtreck, Karl F, Wu, Zhenlong, Fan, Zhen-Chuan
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7963478/
https://ncbi.nlm.nih.gov/pubmed/33587040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.59119
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