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Bardet–Biedl syndrome 3 protein promotes ciliary exit of the signaling protein phospholipase D via the BBSome

Certain ciliary signaling proteins couple with the BBSome, a conserved complex of Bardet–Biedl syndrome (BBS) proteins, to load onto retrograde intraflagellar transport (IFT) trains for their removal out of cilia in Chlamydomonas reinhardtii. Here, we show that loss of the Arf-like 6 (ARL6) GTPase B...

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Publicat a:eLife
Autors principals: Liu, Yan-Xia, Xue, Bin, Sun, Wei-Yue, Wingfield, Jenna L, Sun, Jun, Wu, Mingfu, Lechtreck, Karl F, Wu, Zhenlong, Fan, Zhen-Chuan
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7963478/
https://ncbi.nlm.nih.gov/pubmed/33587040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.59119
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