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Differential scaling of gene expression with cell size may explain size control in budding yeast

Yeast cells must grow to a critical size before committing to division. It is unknown how size is measured. We find that as cells grow, mRNAs for some cell cycle activators scale faster than size, increasing in concentration, while mRNAs for some inhibitors scale slower than size, decreasing in conc...

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Bibliografiske detaljer
Udgivet i:Mol Cell
Main Authors: Chen, Yuping, Zhao, Gang, Zahumensky, Jakub, Honey, Sangeet, Futcher, Bruce
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7963363/
https://ncbi.nlm.nih.gov/pubmed/32246903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.03.012
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