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Differential scaling of gene expression with cell size may explain size control in budding yeast

Yeast cells must grow to a critical size before committing to division. It is unknown how size is measured. We find that as cells grow, mRNAs for some cell cycle activators scale faster than size, increasing in concentration, while mRNAs for some inhibitors scale slower than size, decreasing in conc...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Chen, Yuping, Zhao, Gang, Zahumensky, Jakub, Honey, Sangeet, Futcher, Bruce
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7963363/
https://ncbi.nlm.nih.gov/pubmed/32246903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.03.012
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