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Roles of the CDK Phosphorylation Sites of Yeast Cdc6 in Chromatin Binding and Rereplication
The Saccharomyces cerevisiae Cdc6 protein is crucial for DNA replication. In the absence of cyclin-dependent kinase (CDK) activity, Cdc6 binds to replication origins, and loads Mcm proteins. In the presence of CDK activity, Cdc6 does not bind to origins, and this helps prevent rereplication. CDK act...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2007
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1838967/ https://ncbi.nlm.nih.gov/pubmed/17267692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-06-0544 |
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