Activation of CREB‐mediated autophagy by thioperamide ameliorates β‐amyloid pathology and cognition in Alzheimer’s disease

Alzheimer's disease (AD) is an age‐related neurodegenerative disease, and the imbalance between production and clearance of β‐amyloid (Aβ) is involved in its pathogenesis. Autophagy is an intracellular degradation pathway whereby leads to removal of aggregated proteins, up‐regulation of which m...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Aging Cell
Hlavní autoři: Wang, Jiangong, Liu, Bin, Xu, Yong, Yang, Meizi, Wang, Chaoyun, Song, Mengmeng, Liu, Jing, Wang, Wentao, You, Jingjing, Sun, Fengjiao, Wang, Dan, Liu, Dunjiang, Yan, Haijing
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2021
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7963336/
https://ncbi.nlm.nih.gov/pubmed/33682314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13333
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky