Activation of CREB‐mediated autophagy by thioperamide ameliorates β‐amyloid pathology and cognition in Alzheimer’s disease

Alzheimer's disease (AD) is an age‐related neurodegenerative disease, and the imbalance between production and clearance of β‐amyloid (Aβ) is involved in its pathogenesis. Autophagy is an intracellular degradation pathway whereby leads to removal of aggregated proteins, up‐regulation of which m...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Wang, Jiangong, Liu, Bin, Xu, Yong, Yang, Meizi, Wang, Chaoyun, Song, Mengmeng, Liu, Jing, Wang, Wentao, You, Jingjing, Sun, Fengjiao, Wang, Dan, Liu, Dunjiang, Yan, Haijing
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7963336/
https://ncbi.nlm.nih.gov/pubmed/33682314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13333
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