Early growth response 2 (EGR2) is a novel regulator of the senescence programme

Senescence, a state of stable growth arrest, plays an important role in ageing and age‐related diseases in vivo. Although the INK4/ARF locus is known to be essential for senescence programmes, the key regulators driving p16 and ARF transcription remain largely underexplored. Using siRNA screening fo...

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Détails bibliographiques
Publié dans:Aging Cell
Auteurs principaux: Tyler, Eleanor J., Gutierrez del Arroyo, Ana, Hughes, Bethany K., Wallis, Ryan, Garbe, James C., Stampfer, Martha R., Koh, Jim, Lowe, Robert, Philpott, Michael P., Bishop, Cleo L.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2021
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7963333/
https://ncbi.nlm.nih.gov/pubmed/33547862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13318
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