LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy

Breast cancer brain metastasis (BCBM) is a devastating disease. Radiation therapy remains the mainstay for treatment of this disease. Unfortunately, its efficacy is limited by the dose that can be safely applied. One promising approach to overcoming this limitation is to sensitize BCBMs to radiation...

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Опубликовано в: :Nat Cell Biol
Главные авторы: Chen, Yanke, Jiang, Ting, Zhang, Hongyi, Gou, Xingchun, Han, Cong, Wang, Jianhui, Chen, Ann T., Ma, Jun, Liu, Jun, Chen, Zeming, Jing, Xintao, Lei, Hong, Wang, Zhenzhen, Bao, Youmei, Baqri, Mehdi, Zhu, Yong, Bindra, Ranjit S., Hansen, James E., Dou, Jun, Huang, Chen, Zhou, Jiangbing
Формат: Artigo
Язык:Inglês
Опубликовано: 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7962994/
https://ncbi.nlm.nih.gov/pubmed/33005030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-020-00586-6
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