EMMPRIN regulates tumor growth and metastasis by recruiting bone marrow-derived cells through paracrine signaling of SDF-1 and VEGF

EMMPRIN, a cell adhesion molecule highly expressed in a variety of tumors, is associated with poor prognosis in cancer patients. Mechanistically, EMMPRIN has been characterized to contribute to tumor development and progression by controlling the expression of MMPs and VEGF. In the present study, by...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chen, Yanke, Gou, Xingchun, Kong, Derek Kai, Wang, Xiaofei, Wang, Jianhui, Chen, Zeming, Huang, Chen, Zhou, Jiangbing
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741713/
https://ncbi.nlm.nih.gov/pubmed/26416452
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