EMMPRIN regulates tumor growth and metastasis by recruiting bone marrow-derived cells through paracrine signaling of SDF-1 and VEGF

EMMPRIN, a cell adhesion molecule highly expressed in a variety of tumors, is associated with poor prognosis in cancer patients. Mechanistically, EMMPRIN has been characterized to contribute to tumor development and progression by controlling the expression of MMPs and VEGF. In the present study, by...

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Pubblicato in:Oncotarget
Autori principali: Chen, Yanke, Gou, Xingchun, Kong, Derek Kai, Wang, Xiaofei, Wang, Jianhui, Chen, Zeming, Huang, Chen, Zhou, Jiangbing
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2015
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741713/
https://ncbi.nlm.nih.gov/pubmed/26416452
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