LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy

Breast cancer brain metastasis (BCBM) is a devastating disease. Radiation therapy remains the mainstay for treatment of this disease. Unfortunately, its efficacy is limited by the dose that can be safely applied. One promising approach to overcoming this limitation is to sensitize BCBMs to radiation...

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Detalhes bibliográficos
Publicado no:Nat Cell Biol
Main Authors: Chen, Yanke, Jiang, Ting, Zhang, Hongyi, Gou, Xingchun, Han, Cong, Wang, Jianhui, Chen, Ann T., Ma, Jun, Liu, Jun, Chen, Zeming, Jing, Xintao, Lei, Hong, Wang, Zhenzhen, Bao, Youmei, Baqri, Mehdi, Zhu, Yong, Bindra, Ranjit S., Hansen, James E., Dou, Jun, Huang, Chen, Zhou, Jiangbing
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7962994/
https://ncbi.nlm.nih.gov/pubmed/33005030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-020-00586-6
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