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Structural Basis for the Functional Changes by EGFR Exon 20 Insertion Mutations

SIMPLE SUMMARY: Non-small cell lung cancer (NSCLC) is the most common type of lung cancer that claims the lives of many worldwide. Activating mutations occurring on the epidermal growth factor receptor (EGFR) protein have been associated with the pathogenesis of NSCLC, among which exon 20 insertion...

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Publicado en:Cancers (Basel)
Main Authors: Tamirat, Mahlet Z., Kurppa, Kari J., Elenius, Klaus, Johnson, Mark S.
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7961794/
https://ncbi.nlm.nih.gov/pubmed/33807850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13051120
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