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Structural characterization of EGFR exon 19 deletion mutation using molecular dynamics simulation
Epidermal growth factor receptor (EGFR) is a tyrosine kinase receptor important in diverse biological processes including cell proliferation and survival. Upregulation of EGFR activity due to over-expression or mutation is widely implicated in cancer. Activating somatic mutations of the EGFR kinase...
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| I publikationen: | PLoS One |
|---|---|
| Huvudupphovsmän: | , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Public Library of Science
2019
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6752865/ https://ncbi.nlm.nih.gov/pubmed/31536605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0222814 |
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