Human pluripotent stem-cell-derived alveolar organoids for modeling pulmonary fibrosis and drug testing

Detailed understanding of the pathogenesis and development of effective therapies for pulmonary fibrosis (PF) have been hampered by lack of in vitro human models that recapitulate disease pathophysiology. In this study, we generated alveolar organoids (AOs) derived from human pluripotent stem cells...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Discov
Prif Awduron: Kim, Jung-Hyun, An, Geun Ho, Kim, Ji-Young, Rasaei, Roya, Kim, Woo Jin, Jin, Xiong, Woo, Dong-Hun, Han, Choongseong, Yang, Se-Ran, Kim, Jong-Hoon, Hong, Seok-Ho
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2021
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7961057/
https://ncbi.nlm.nih.gov/pubmed/33723255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-021-00439-7
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