Diesel Particulate Matter 2.5 Induces Epithelial-to-Mesenchymal Transition and Upregulation of SARS-CoV-2 Receptor during Human Pluripotent Stem Cell-Derived Alveolar Organoid Development

Growing evidence links prenatal exposure to particulate matter (PM2.5) with reduced lung function and incidence of pulmonary diseases in infancy and childhood. However, the underlying biological mechanisms of how prenatal PM2.5 exposure affects the lungs are incompletely understood, which explains t...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Jung-Hyun Kim, Jeeyoung Kim, Woo Jin Kim, Yung Hyun Choi, Se-Ran Yang, Seok-Ho Hong
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI AG 2020-11-01
סדרה:International Journal of Environmental Research and Public Health
נושאים:
dPM2.5
EMT
alveolar organoid
human pluripotent stem cells
fibrosis
גישה מקוונת:https://www.mdpi.com/1660-4601/17/22/8410
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