Human pluripotent stem-cell-derived alveolar organoids for modeling pulmonary fibrosis and drug testing

Detailed understanding of the pathogenesis and development of effective therapies for pulmonary fibrosis (PF) have been hampered by lack of in vitro human models that recapitulate disease pathophysiology. In this study, we generated alveolar organoids (AOs) derived from human pluripotent stem cells...

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Detalhes bibliográficos
Publicado no:Cell Death Discov
Main Authors: Kim, Jung-Hyun, An, Geun Ho, Kim, Ji-Young, Rasaei, Roya, Kim, Woo Jin, Jin, Xiong, Woo, Dong-Hun, Han, Choongseong, Yang, Se-Ran, Kim, Jong-Hoon, Hong, Seok-Ho
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7961057/
https://ncbi.nlm.nih.gov/pubmed/33723255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-021-00439-7
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