Human pluripotent stem-cell-derived alveolar organoids for modeling pulmonary fibrosis and drug testing

Detailed understanding of the pathogenesis and development of effective therapies for pulmonary fibrosis (PF) have been hampered by lack of in vitro human models that recapitulate disease pathophysiology. In this study, we generated alveolar organoids (AOs) derived from human pluripotent stem cells...

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Veröffentlicht in:Cell Death Discov
Hauptverfasser: Kim, Jung-Hyun, An, Geun Ho, Kim, Ji-Young, Rasaei, Roya, Kim, Woo Jin, Jin, Xiong, Woo, Dong-Hun, Han, Choongseong, Yang, Se-Ran, Kim, Jong-Hoon, Hong, Seok-Ho
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7961057/
https://ncbi.nlm.nih.gov/pubmed/33723255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-021-00439-7
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