Circulating mucosal-associated invariant T cells identify patients responding to anti-PD-1 therapy

Immune checkpoint inhibitors are used for treating patients with metastatic melanoma. Since the response to treatment is variable, biomarkers are urgently needed to identify patients who may benefit from such therapy. Here, we combine single-cell RNA-sequencing and multiparameter flow cytometry to a...

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Publicado no:Nat Commun
Main Authors: De Biasi, Sara, Gibellini, Lara, Lo Tartaro, Domenico, Puccio, Simone, Rabacchi, Claudio, Mazza, Emilia M. C., Brummelman, Jolanda, Williams, Brandon, Kaihara, Kelly, Forcato, Mattia, Bicciato, Silvio, Pinti, Marcello, Depenni, Roberta, Sabbatini, Roberto, Longo, Caterina, Dominici, Massimo, Pellacani, Giovanni, Lugli, Enrico, Cossarizza, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7961017/
https://ncbi.nlm.nih.gov/pubmed/33723257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-21928-4
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