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Mutation of Framework Residue H71 Results in Different Antibody Paratope States in Solution
Characterizing and understanding the antibody binding interface have become a pre-requisite for rational antibody design and engineering. The antigen-binding site is formed by six hypervariable loops, known as the complementarity determining regions (CDRs) and by the relative interdomain orientation...
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| Izdano u: | Front Immunol |
|---|---|
| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Frontiers Media S.A.
2021
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7960778/ https://ncbi.nlm.nih.gov/pubmed/33737932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.630034 |
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