Exploration of a Sequential Gp140-Gp145 Immunization Regimen with Heterologous Envs to Induce a Protective Cross-Reactive HIV Neutralizing Antibody Response In Non-human Primates

Raising a heterologous tier 2 neutralizing antibody (nAb) response remains a daunting task for HIV vaccine development. In this study, we explored the utility of diverse HIV-1 envelope (Env) immunogens in a sequential immunization scheme as a solution to this task. This exploration stemmed from the...

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Detalhes bibliográficos
Publicado no:Virol Sin
Main Authors: Ding, Xiangqing, Cao, Kangli, Wang, Jing, Wan, Yanmin, Chen, Qinyun, Ren, Yanqin, Zheng, Yongtang, Zhu, Mingzhao, Tian, Renrong, Wang, Wenjun, Zhao, Chen, Zhang, Xiaoyan, Xu, Jianqing
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Singapore 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7959301/
https://ncbi.nlm.nih.gov/pubmed/33723807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12250-021-00361-3
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