Protective mechanism of kaempferol against Aβ(25-35)-mediated apoptosis of pheochromocytoma (PC-12) cells through the ER/ERK/MAPK signalling pathway

INTRODUCTION: Progressive accumulation of amyloid-β (Aβ) is a pathological trait of Alzheimer’s disease (AD). Amyloid-β increases free radical production in neuronal cells, leading to neuronal cell death. Hormone replacement therapy can reduce the incidence of AD, and oestrogen significantly improve...

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Detalhes bibliográficos
Publicado no:Arch Med Sci
Main Authors: Zhang, Ning, Xu, Hongdan, Wang, Yueying, Yao, Yuan, Liu, Guoliang, Lei, Xia, Sun, Huifeng, Wu, Xiuhong, Li, Jianmin
Formato: Artigo
Idioma:Inglês
Publicado em: Termedia Publishing House 2020
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7959041/
https://ncbi.nlm.nih.gov/pubmed/33747277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/aoms.2020.98199
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