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Tyrosine-specific MAPK phosphatases and the control of ERK signaling in PC12 cells

BACKGROUND: Spatio-temporal control of extracellular signal-regulated kinase (ERK) activity, a critical determinant of the cell's response to growth factors, requires timely dephosphorylation of its regulatory tyrosine and/or threonine residue by MAPK phosphatases. We studied the physiological...

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Detalhes bibliográficos
Main Authors: Noordman, Yvet E, Jansen, Patrick AM, Hendriks, Wiljan JAJ
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1761141/
https://ncbi.nlm.nih.gov/pubmed/17224080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-2187-1-4
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