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Discovery and engineering of colchicine alkaloid biosynthesis
Few complete pathways are established for the biosynthesis of medicinal compounds from plants. Accordingly, many plant-derived therapeutics are isolated directly from medicinal plants or plant cell culture.(1) A lead example is colchicine, an FDA-approved treatment for inflammatory disorders that is...
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| Published in: | Nature |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7958869/ https://ncbi.nlm.nih.gov/pubmed/32699417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2546-8 |
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