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A43 LONG-TERM EFFICACY AND SAFETY OF OBETICHOCLIC ACID IN PRIMARY BILIARY CHOLANGITIS: RESPONDER ANALYSIS OF OVER 5 YEARS OF TREATMENT IN THE POISE TRIAL

BACKGROUND: Obeticholic acid (OCA), a potent farnesoid X receptor agonist, is approved as second-line treatment for primary biliary cholangitis (PBC) in patients with an incomplete response or intolerance to ursodeoxycholic acid. AIMS: We evaluated the effect of OCA in PBC patients enrolled in the P...

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Detalhes bibliográficos
Publicado no:J Can Assoc Gastroenterol
Main Authors: Hirschfield, G, Jones, D, Carbone, M, Bowlus, C L, Nevens, F, Kremer, A E, Liberman, A, MacConell, L, Hansen, B E
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7958753/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwab002.041
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