Reduction and stabilization of bilirubin with obeticholic acid treatment in patients with primary biliary cholangitis

BACKGROUND & AIMS: Total bilirubin is a predictor of survival in primary biliary cholangitis, with the main elevated component being direct bilirubin. The purpose of this post hoc analysis was to assess the efficacy and safety of obeticholic acid across quartiles of varying baseline levels of di...

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Vydáno v:Liver Int
Hlavní autoři: Parés, Albert, Shiffman, Mitchell, Vargas, Victor, Invernizzi, Pietro, Malecha, Elizabeth S., Liberman, Alexander, MacConell, Leigh, Hirschfield, Gideon
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
Gut‐liver Axis, Immunology, Immune Mediated and Cholestatic Diseases
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7317821/
https://ncbi.nlm.nih.gov/pubmed/32145129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.14429
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