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Obeticholic acid is associated with improvements in AST-to-platelet ratio index and GLOBE score in patients with primary biliary cholangitis

BACKGROUND & AIMS: Biochemical markers, including GLOBE score and aspartate aminotransferase-to-platelet ratio index (APRI), are used to stratify risk in patients with primary biliary cholangitis (PBC). This study aimed to evaluate the effects of obeticholic acid (OCA) on categorical shifts in G...

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Detalhes bibliográficos
Publicado no:JHEP Rep
Main Authors: Harms, Maren H., Hirschfield, Gideon M., Floreani, Annarosa, Mayo, Marlyn J., Parés, Albert, Liberman, Alexander, Malecha, Elizabeth Smoot, Pencek, Richard, MacConell, Leigh, Hansen, Bettina E.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7724188/
https://ncbi.nlm.nih.gov/pubmed/33319187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhepr.2020.100191
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