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Obeticholic acid is associated with improvements in AST-to-platelet ratio index and GLOBE score in patients with primary biliary cholangitis

BACKGROUND & AIMS: Biochemical markers, including GLOBE score and aspartate aminotransferase-to-platelet ratio index (APRI), are used to stratify risk in patients with primary biliary cholangitis (PBC). This study aimed to evaluate the effects of obeticholic acid (OCA) on categorical shifts in G...

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Détails bibliographiques
Publié dans:JHEP Rep
Auteurs principaux: Harms, Maren H., Hirschfield, Gideon M., Floreani, Annarosa, Mayo, Marlyn J., Parés, Albert, Liberman, Alexander, Malecha, Elizabeth Smoot, Pencek, Richard, MacConell, Leigh, Hansen, Bettina E.
Format: Artigo
Langue:Inglês
Publié: Elsevier 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7724188/
https://ncbi.nlm.nih.gov/pubmed/33319187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhepr.2020.100191
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