Elevated cerebrospinal fluid cytokine levels in tuberculous meningitis predict survival in response to dexamethasone

Adjunctive treatment with antiinflammatory corticosteroids like dexamethasone increases survival in tuberculosis meningitis. Dexamethasone responsiveness associates with a C/T variant in Leukotriene A4 Hydrolase (LTA4H), which regulates expression of the proinflammatory mediator leukotriene B(4) (LT...

詳細記述

保存先:
書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Whitworth, Laura J., Troll, Rajan, Pagán, Antonio J., Roca, Francisco J., Edelstein, Paul H., Troll, Mark, Tobin, David M., Phu, Nguyen Hoan, Bang, Nguyen Duc, Thwaites, Guy E., Thuong, Nguyen Thuy Thuong, Sewell, Roger F., Ramakrishnan, Lalita
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2021
主題:
Biological Sciences
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7958233/
https://ncbi.nlm.nih.gov/pubmed/33658385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2024852118
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