ADAM10 Plasma and CSF Levels Are Increased in Mild Alzheimer’s Disease

ADAM10 is the main α-secretase that participates in the non-amyloidogenic cleavage of amyloid precursor protein (APP) in neurons, inhibiting the production of β-amyloid peptide (Aβ) in Alzheimer’s disease (AD). Strong recent evidence indicates the importance of the localization of ADAM10 for its act...

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Foilsithe in:Int J Mol Sci
Main Authors: Pereira Vatanabe, Izabela, Peron, Rafaela, Mantellatto Grigoli, Marina, Pelucchi, Silvia, De Cesare, Giulia, Magalhães, Thamires, Manzine, Patricia Regina, Figueredo Balthazar, Marcio Luiz, Di Luca, Monica, Marcello, Elena, Cominetti, Marcia Regina
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2021
Ábhair:
Communication
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7957802/
https://ncbi.nlm.nih.gov/pubmed/33670873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052416
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