ADAM10 Plasma and CSF Levels Are Increased in Mild Alzheimer’s Disease

ADAM10 is the main α-secretase that participates in the non-amyloidogenic cleavage of amyloid precursor protein (APP) in neurons, inhibiting the production of β-amyloid peptide (Aβ) in Alzheimer’s disease (AD). Strong recent evidence indicates the importance of the localization of ADAM10 for its act...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Autores principales: Pereira Vatanabe, Izabela, Peron, Rafaela, Mantellatto Grigoli, Marina, Pelucchi, Silvia, De Cesare, Giulia, Magalhães, Thamires, Manzine, Patricia Regina, Figueredo Balthazar, Marcio Luiz, Di Luca, Monica, Marcello, Elena, Cominetti, Marcia Regina
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7957802/
https://ncbi.nlm.nih.gov/pubmed/33670873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052416
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