ADAM10 Plasma and CSF Levels Are Increased in Mild Alzheimer’s Disease

ADAM10 is the main α-secretase that participates in the non-amyloidogenic cleavage of amyloid precursor protein (APP) in neurons, inhibiting the production of β-amyloid peptide (Aβ) in Alzheimer’s disease (AD). Strong recent evidence indicates the importance of the localization of ADAM10 for its act...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Pereira Vatanabe, Izabela, Peron, Rafaela, Mantellatto Grigoli, Marina, Pelucchi, Silvia, De Cesare, Giulia, Magalhães, Thamires, Manzine, Patricia Regina, Figueredo Balthazar, Marcio Luiz, Di Luca, Monica, Marcello, Elena, Cominetti, Marcia Regina
Format: Artigo
Langue:Inglês
Publié: MDPI 2021
Sujets:
Communication
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7957802/
https://ncbi.nlm.nih.gov/pubmed/33670873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22052416
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