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Self‐assembly of multi‐component mitochondrial nucleoids via phase separation

Mitochondria contain an autonomous and spatially segregated genome. The organizational unit of their genome is the nucleoid, which consists of mitochondrial DNA (mtDNA) and associated architectural proteins. Here, we show that phase separation is the primary physical mechanism for assembly and size...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Feric, Marina, Demarest, Tyler G, Tian, Jane, Croteau, Deborah L, Bohr, Vilhelm A, Misteli, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7957436/
https://ncbi.nlm.nih.gov/pubmed/33619770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020107165
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